Annihilation is a 2014 novel by Jeff VanderMeer. It is the first in a series of three books called the Southern Reach Trilogy. The book describes a team of four women (a biologist, an anthropologist, a psychologist, and a surveyor) who set out into an area known as Area X. The area is abandoned and cut off from the rest of civilization. They are the 12th expedition; the previous expeditions have been fraught with disappearances, suicides, aggressive cancers, and mental trauma. The novel won the 2014 Nebula Award for Best Novel and the 2014 Shirley Jackson Award for best novel.A film based on the novel, starring Natalie Portman, was released by Paramount Pictures on February 23, 2018.